Binotal: Benefits, Dosage, Side Effects

Published: May 25, 2020
Written by: Mutia Rahayu | Reviewed by: Team of Doctors

ZREHAB.Com – What drug binotals? Binotal is a drug containing the active ingredient Ampicillin. This drug belongs to the penicillin class of antibiotics used to treat certain bacterial infections.

Find out more about Binotal starting from its benefits, side effects, dosage, instructions for use, and more through this article!

Summary of Binotal Drug Information

Drug Name Binotal Drug Ingredients Ampicillin trihydrate Drug Class Penicillin Antibiotic Category Prescription Drugs Benefits Drugs Cope with certain bacterial infections Consumed by adults and children Contraindications Hypersensitivity Drug Preparations Tablets

Binotal Content and Methods

Binotal contains Ampicillin which is a drug from the penicillin class of antibiotics. As we know, antibiotics are drugs used to treat infections caused by bacteria.

These drugs work by interfering with the ability of bacteria to form cell walls. Ampicillin can cause small holes in the bacterial cell walls and this can kill the bacteria that cause infection. Ampicillin is included in a broad-spectrum antibiotic that can react to gram-positive and gram-negative bacteria.

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Benefits of Binotal

In general, the benefits of Binotal are to treat infections caused by bacteria. Here are some bacterial infections that are generally treated using Binotal:

  • Respiratory infections such as bronchitis and pneumonia
  • Urinary tract infection
  • Sinusitis
  • Otitis media (bacterial ear infection)
  • Gastrointestinal infections

Binotal dose

Binotal is present in Binotal tablets Binotal 1000 mg and Binotal 500 mg. Binotal 1000 is Binotal tablet containing 1000 mg of Ampicillin in each tablet, while Binotal 500 mg contains 500 mg of Ampicillin in each tablet.

Here are the recommended Binotal dosages:

1. Binotal dosage for adults or children weighing over 20 kg

  • Urinary or gastrointestinal tract infections: 500 mg, given 4 times daily in equal doses and distances.
  • Gonorrhea: a single dose of 3.5 grams, given together with the recommended 1 g of probenecid.
  • Respiratory tract infections: 250 mg, given 4 times daily at the same dose and distance.

2. Dosage for children weighing 20 kg or less

  • Urinary or gastrointestinal tract infection: total dose 100 mg /kg body weight, divided into 4 doses and given evenly spaced.
  • Respiratory tract infections: total dose 50 mg /kg body weight, divided into 3 or 4 doses and given at equal intervals.

The doses above are the doses that are usually given. The dose may be added if the infection is chronic or severe. Use Binotal according to the dose prescribed and never change the dose without consulting a doctor or pharmacist.

Binotal Usage Instructions

Use of the drug Binotal should be used in accordance with the rules. Here are the instructions for using Binotal:

  • Binotal is used at least 30 to 60 minutes before meals.
  • Caplet binotal and syrup are consumed by swallowing directly with water.
  • Use the drug Binotal according to the recommended dosage.
  • Use the drug at the same time every day.
  • If you miss a dose, take it as soon as you remember. However, if it is closer to the time of the next dose, then it is sufficient to take the next dose.
  • If accidentally using this drug exceeds the recommended dose, consult a doctor immediately.

Binotal Storage Guide

Store the drug Binotal the same age as the instructions for storage to prevent the drug from spoiling and decreasing its effectiveness. Following are the Binotals storage instructions that must be considered:

  • Store the drug Binotal at temperatures below 30 ° C.
  • Store the drug Binotal in a dry and not damp place, do not store it in the bathroom.
  • Avoid the drug Binotal from direct light or sunlight.
  • Avoid the drug Binotal out of reach of children and pets.
  • If the drug has entered the expiration period, do not throw away the drug carelessly, discuss with the pharmacist the instructions for disposal of this drug.

Binotal Side Effects

Each drug has the potential to cause side effects, as well as Binotal. Binotal side effects that may occur include:

  • Diarrhea
  • Nausea and vomiting
  • Skin rash and itching
  • Candida yeast overgrowth

Other side effects that may occur but are less common include:

  • Intestinal inflammation or colitis
  • Liver disorders
  • Red blood cell problems that can cause unexplained bruising, sore throat, fever, and infections.
  • Inflammation of the liver or kidneys.

The above side effects do not always occur. Side effects can occur due to excessive drug use, drug interactions, long-term use, or because of the specific condition of each patient which of course varies.

If you experience symptoms of serious side effects or allergic reactions, immediately consult a doctor to get further treatment and stop using the drug.

Binotal Drug Interactions

Drug interactions can occur when Binotal is used together with certain other types of drugs. Drug interactions cause drug effectiveness to decrease and can increase the potential for side effects. The following are types of drugs that should not be used together with Binotal:

  • Painkillers
  • Oral contraceptives
  • Anticoagulants
  • Methotrexate
  • Vaccine

The above list may not be an exhaustive list. Tell your doctor if you are currently taking or recently taking certain drugs, including prescription, non-prescription drugs, to herbal medicines.

Alcohol consumption can also cause drug interactions, so it should be avoided. Also discuss with your doctor about the types of food or drinks that should be avoided during the use of the drug Binotal to avoid drug interactions.

Binotal Warning and Attention

Binotal drugs are included in the category of hard drugs whose use must be through a doctor’s prescription. Here are some other things that need warning and attention during the use of the drug Binotal:

  • Do not use the drug Binotal in patients who are hypersensitive to Ampicillin, other penicillin type drugs, and other components contained in this drug.
  • Be careful using Binotal in patients who have kidney and liver problems.
  • Use caution for use of Binotal in patients suspected of having conditions such as glandular fever, acute or chronic lymphoid leukemia.
  • The use of this drug in pregnant and lactating women is known to be harmless. Before using this medicine, make sure you tell your doctor if you are pregnant, breastfeeding, or planning a pregnancy.


  • Ampicillin (Penbritin): an antibiotic to treat bacterial infections – 23 Mei 2019
  • Ampicillin – accessed 23 May 2019
  • Binotal Uses – accessed on 23 May 2019
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